John R Yates III

John R Yates III, Ph.D.

Department of Chemical Physiology
California Campus
Laboratory Website
Scripps VIVO Scientific Profile
(858) 784-8862

Scripps Research Joint Appointments

Department of Molecular and Cellular Neuroscience
Faculty, Graduate Program


M.S., Chemistry, University of Maine, 1983
Ph.D., Chemistry, University of Virginia, 1987
B.A., Zoology, University of Maine, 1980

Awards and Honors

1996                 American Society for Mass Spectrometry Research Award

1998                 Pehr Edman Award in Protein Chemistry

2001                 Genome Technologies All Star in Proteomics

2004                 Biemann Award, American Society for Mass Spectrometry

2005                 HUPO Distinguished Achievement Award in Proteomics, Munich, Germany

2006                 Herbert Sober Award Lecture, American Society of Biochemistry and Molecular Biology, San Francisco

2006                 Christian Anfinsen Award, The Protein Society, San Diego

2011                Top 100 Chemists, 2000-2010, Ranked by Citation Impact, Science Watch

2013                #1 on List of Most Influential in Analytical Chemistry, The Analytical Scientist 10/30/2013

2013                List Of Most Highly Influential Biomedical Researchers, 1996-2011, European J. Clinical Investigation 2013, 43, 1339-1365

2015                ACS Award in Analytical Chemistry

2015                Ralph Adams Award in Bioanalytical Chemistry

2015                Thomson Reuters List of Highly Cited Scientists

Selected Publication

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.
Nature. 2015 Dec 24;528(7583):510-6. doi: 10.1038/nature15729. Epub 2015 Nov 30.

Pulsed Azidohomoalanine Labeling in Mammals (PALM) Detects Changes in Liver-Specific LKB1 Knockout Mice.
J Proteome Res. 2015 Nov 6;14(11):4815-22. doi: 10.1021/acs.jproteome.5b00653. Epub 2015 Oct 26.

Pivotal role of computers and software in mass spectrometry – SEQUEST and 20 years of tandem MS database searching.
J Am Soc Mass Spectrom. 2015 Nov;26(11):1804-13. doi: 10.1007/s13361-015-1220-0. Epub 2015 Aug 19.

From raw data to biological discoveries: a computational analysis pipeline for mass spectrometry-based proteomics.
J Am Soc Mass Spectrom. 2015 Nov;26(11):1820-6. doi: 10.1007/s13361-015-1161-7. Epub 2015 May 22.

Global quantitative analysis of phosphorylation underlying phencyclidine signaling and sensorimotor gating in the prefrontal cortex.
Mol Psychiatry. 2016 Feb;21(2):205-15. doi: 10.1038/mp.2015.41. Epub 2015 Apr 14.

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia.
Mol Psychiatry. 2015 Mar;20(3):361-8. doi: 10.1038/mp.2014.22. Epub 2014 Apr 1.

Extremely long-lived nuclear pore proteins in the rat brain.
Science. 2012 Feb 24;335(6071):942. doi: 10.1126/science.1217421. Epub 2012 Feb 2.

The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors.
Neuron. 2015 Aug 19;87(4):764-80. doi: 10.1016/j.neuron.2015.08.007.

A proteomic view of the Plasmodium falciparum life cycle.
Nature. 2002 Oct 3;419(6906):520-6.

Large-scale analysis of the yeast proteome by multidimensional protein identification technology.
Nat Biotechnol. 2001 Mar;19(3):242-7.